9th World Biomaterials Congress (June 1-5, 2012, Chengdu, China, http://www.wbc2012.com/ ) 42.4. The Roles of water molecules in the biointerface - clarification of biocompatibility mechanisms
Chair: Masaru Tanaka, Department of Biochemical Engineering, Yamagata University, Japan Co-Chairs: Shigeaki Morita, EcoTopia Science Institute, Nagoya University, Japan; Tomohiro Hayashi, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Japan
Organizers: Masaru Tanaka, Department of Biochemical Engineering, Yamagata University, Japan; Shigeaki Morita, EcoTopia Science Institute, Nagoya University, Japan; Tomohiro Hayashi, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Japan
Synopsis: A numberof polimeric biomaterials have been proposed, including hydrophilic surfaces, phase-separated microdomain surfaces, and bioinspired biomembrane-like surfaces. It has not been clearly elucidated which mechanism(s) is responsible for biocompatibility on a molecular level, although many theoretical and experimental efforts have been devotedto this mechanism.Water interactions have been recognized as a fundamental part of the biological response to contact with polymers. The study of the dynamics and structure of hydrated polymers at biointerfaces encompasses a wide range of techniques. This symposium is to give an overview of the recent progress in the quantitative description of biocompatibility mechanisms driven by novel approaches.
Keynote speaker: Michael Grunze, Angewandte Physikalische Chemie, Universit of Heidelberg, Germany
Lecture Title: Water molecules at the cell and biomaterial interface - Occam's Razor applied to the myths of interfacial water
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